RVCL is an Ultra-Rare Genetic Disease

RVCL is often misdiagnosed because its symptoms vary from patient to patient and resemble those of other diseases. We aim to find a cure.

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What is RVCL?

RVCL is an ultra-rare disease that is characterized by the deterioration of small blood vessels. The condition is often misdiagnosed because symptoms vary from patient to patient and resemble other diseases. RVCL causes vascular dementia due to a single-gene mutation, and vascular dementia is included among Alzheimer’s disease-related dementias.


RVCL is a rare genetic condition that causes deterioration of small blood vessels

Early symptoms typically include vision loss and mild strokes to the brain

Symptoms typically appear in patients between the ages of 30 and 50

Often misdiagnosed as multiple sclerosis, brain cancer, brain tumors, diabetes, or undiagnosed

There is meaningful research underway to find treatments or a cure for RVCL

Identifying more patients with RVCL is essential to find a treatment or cure

Be a part of the cure

Legitimate scientific research takes funding for reagents, supplies, equipment, and so much more.
No matter the amount, the entirety of your donation will be utilized to further our efforts in finding a cure.


About The Foundation

The Clayco Foundation is a 501(c)(3) organization dedicated to providing education and support for patients, researchers, and doctors. Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL) is a rare genetic disorder that causes progressive damage to the brain, eye, kidney, and liver. There is currently no cure for RVCL, something The Clayco Foundation aims to change.

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