Retinal Multimodal Imaging in RVCL Retinal multimodal imaging in RVCL Dr. Rajendra Apte, M.D., Ph.D. Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is a rare autosomal dominant vascular dementia and retinopathy. Histologically. RVCL causes a disease…
Exploring RVCL-Mutated TREX1 Activities in the Nucleus of Cells Exploring RVCL-Mutated TREX1 Activities in the Nucleus of Cells: Interplay with Nuclear Envelope (NE) Rupture, DNA Damage & Innate Immune Sensors The pathology in RVCL is speculated to stem from…
Developing a Microfluidic Model of RVCL Developing a microfluidic model of RVCL Dr. David Hunt, M.D., Ph.D. Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is a devastating and untreatable systemic monogenic microangiopathy caused by frameshift mutations in…
